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pentobarbital will lower the level or influence of elbasvir/grazoprevir by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. The therapeutic impact of elbasvir/grazoprevir might be minimized if coadministered with potent CYP3A inducers which is hence contraindicated.benzhydrocodone/acetaminophen and pentobarbital both equall